05 Jul 2018 --- The inclusion of nuts in a regular diet significantly improves the quality and function of human sperm, according to results of a randomized trial which measured conventional semen parameters and molecular changes over a 14-week study period. The investigators say the findings “support a beneficial role for chronic nut consumption in sperm quality” and reflect a research need for further male-specific dietary recommendations.
According to Dr. Albert Salas-Huetos from the Human Nutrition Unit of the Universitat Rovira i Virgil in Reus, Spain, the study was performed against a background of general decline in quantity and quality of human sperm, attributed in industrialized countries to “pollution, smoking and trends toward a western-style diet.”
In this study subjects randomized to the nut group had significant improvements in their sperm count, vitality, motility and morphology (shape); these were consistent with improvements found in other recent studies with diets rich in omega 3, antioxidants (e.g., vitamin C and E, selenium and zinc) and folate. Nuts are dense foods containing many of these nutrients and other phytochemicals.
The study was a 14-week randomized clinical trial in which 119 healthy young men aged 18-35 were allocated to either their usual western-style diet supplemented with 60 grams/day of mixed almonds, hazelnuts and walnuts, or their usual western-style diet without nuts. In its analysis the study recorded not just sperm parameters (according to WHO benchmarks) but also changes in several molecular factors, including sperm DNA fragmentation. Sperm and blood samples were analyzed at baseline and after 14 weeks of intervention.
Results found significantly higher levels of sperm count, vitality, motility and morphology in the men randomized to the 60 g/day nut diet than in those following their usual diets free of nuts. Improvements in the former group were by around 16 percent in sperm count, 4 percent in sperm vitality, 6 percent in sperm motility and 1 percent in morphology. These four parameters, explains Salas-Huetos, are all associated with male fertility.
Moreover, the subjects in the nut group also showed a significant reduction in their levels of sperm DNA fragmentation, a parameter closely associated with male infertility. Indeed, it was this change in the level of DNA fragmentation in the sperm cells by which the investigators explained, at least in part, the improvement in sperm count, motility and morphology.
Although these are statistically significant results from a randomized trial with a high level of scientific evidence, Salas-Huetos emphasized that subjects in the study were all healthy and apparently fertile men following a western-style diet. He thus warned that results cannot be extrapolated to the general population.
So should men hoping to conceive a baby – either naturally or with IVF – add nuts to their everyday diet?
“We can't yet say that based solely on the results of this study. But evidence is accumulating in the literature that healthy lifestyle changes such as following a healthy dietary pattern might help conception – and of course, nuts are a key component of a Mediterranean healthy diet,” says Salas-Huetos.
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