Weight Management

US study uncovers "continued" use of harmful ingredients in OTC dietary supplements

15 Oct 2018 --- Potentially harmful active pharmaceuticals continue to be identified in US over-the-counter (OTC) dietary supplements commonly marketed for sexual enhancement, weight loss or muscle building, according to a study published in JAMA. The researchers analyzed US Food and Drug Administration (FDA) warnings from 2007 through 2016 to show that unapproved pharmaceutical ingredients were identified in 776 dietary supplements. In response, US health bodies and trade associations are calling for consumer caution and reform to ensure supplements are free from pharmaceutical contamination.

Obesity could overtake smoking as biggest preventable cause of cancer in women, says UK charity

24 Sep 2018 --- A new report by Cancer Research UK has put forward that obesity will overtake smoking as the biggest preventable cause of cancer among UK women in 25 years’ time. According to the report, by 2035, 10 percent of cancers in women (around 25,000 cases) could be caused by smoking and 9 percent (around 23,000 cases) by excess weight. If trends continue as projected, excess weight could cause even more cases of cancer than smoking in women by 2043.

1 in 4 adults physically inactive and at risk of disease, says WHO

05 Sep 2018 --- More than one in four adults globally – amounting to 1.4 billion people – are physically not active enough, with inactivity levels reaching one in three adults in some countries, new data published in The Lancet Global Health show. Policies to increase the physical activity levels of populations need to be prioritized and scaled up urgently to stave off the risk of poor health, note the involved World Health Organization experts. Regular physical activity is proven to help prevent and treat noncommunicable diseases (NCDs) such as heart disease, stroke, diabetes and different types of cancer. It has also been linked to improved mental health, quality of life and well-being. Moreover, it helps prevent hypertension and obesity.

Restricting food intake to 10 hours a day can lead to better health, research suggests

04 Sep 2018 --- Mice lacking the biological clocks thought to be necessary for a healthy metabolism can still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window, scientists at the Salk Institute have found. The research, which appeared in the journal Cell Metabolism, suggests that the health problems associated with disruptions to animals' 24-hour rhythms of activity and rest – which in humans is linked to eating for most of the day or doing shift work – can be corrected by eating all calories within a 10-hour window.

Chinese plant-substance holds potential for weight loss treatments, study finds

03 Sep 2018 --- A plant-derived substance – celastrol – widely used in traditional Chinese medicine has demonstrated promising weight loss effects in a study published in Diabetes. If celastrol also proves effective in clinical trials, it could offer a new option for the treatment of obesity, the researchers say.

Gut bacteria and caloric restriction hold potential for obesity-fighting drug, mouse study says

31 Aug 2018 --- Mice with a lower calorie intake live longer and are both healthier and leaner, research has generally determined, and now, a study may have found the reason for this positive effect. The researchers identified that much of it is down to gut microbial communities and how they affect the immune system. The researchers hope that their work, published in Cell Metabolism, may one day make it possible to treat obese people with a drug that simulates caloric restriction, following the team uncovering compounds that can mimic caloric restriction.

Obesity closely linked to cognitive and neurological traits, research finds

29 Aug 2018 --- Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to researchers at the Montreal Neurological Institute and Hospital. Their comments came after research found that people with higher a body mass index (BMI) showed reduced cognitive flexibility, ability to delay gratification, visuospatial ability and verbal memory.

“Demonization” of sugar hinders the fight against obesity, warns US nutritionist 

29 Aug 2018 --- “It’s not what one eats that causes obesity, but what one’s body does with what is eaten,” says Edward Archers, Ph.D., Physiologist and Nutrition Scientist. Over the past 50 years researchers, clinicians, health organizations and lobby groups have waged war on sugar, along with other dietary factors, but Archer coins this over emphasis on diet for health as “diet-centrism.” Diet is a trivial factor in metabolic health, positions Archer. Instead, a lack of physical activity is the most important factor for metabolic health.

Cedars-Sinai researchers develop “more accurate” measure of body fat

28 Aug 2018 --- Researchers at Cedars-Sinai have developed what they say is a more straightforward and more accurate method of estimating body fat than the widely used body mass index (BMI), with the goal of better understanding obesity. Coined the relative fat mass index (RFM), the new method uses only height and waist circumference measurements.

Low carbohydrate diets are unsafe, researchers warn

28 Aug 2018 --- Low carbohydrate diets are unsafe and should be avoided, according to a large study presented today at the ESC Congress 2018, the annual meeting of the European Society of Cardiology.

Lorcaserin tipped as weight-loss “holy grail” in fight against obesity

27 Aug 2018 --- Investigators are reporting that for the first time, a weight loss drug has done its job without increasing the incidence of heart attacks, strokes and death from heart disease in a population of people who are especially at risk for cardiovascular events. Subsequently, some health experts are now hailing it a potential “holy grail” in the battle with obesity, due to it not increasing the risk of serious heart problems.

Consuming milk at breakfast found to lower blood glucose throughout the day

20 Aug 2018 --- Consuming milk with breakfast cereal helps reduce postprandial blood glucose concentration compared with water, while a high dairy protein concentration also reduces postprandial blood glucose concentration compared with normal dairy protein concentration, according to a new study published in the Journal of Dairy Science. The high-protein treatment also decreased appetite after the second meal compared with the low-protein equivalent. As a result, this breakfast routine may provide benefits for the management of Type 2 diabetes, the researchers say.

Low-carb diets could shorten life by four years, warns Lancet study

17 Aug 2018 --- Following a low-carb diet could shorten life expectancy by four years, suggests new research published in The Lancet Public Health. The high levels of animal fats and proteins that often replace carbohydrates in typical low-carb diets appear to be associated with the higher risk of mortality. Eating more plant-based proteins and fats in place of carbohydrates was linked to lower mortality and even reversed the greater mortality risk.

Molecular switch may serve as new target point for obesity and diabetes therapies, says study

16 Aug 2018 --- A mechanism of the PI3KC2A kinase enzyme may have significance for the future development of therapies against cancer, obesity and diabetes, research published in Molecular Cell has found. The study highlights how if specific signaling cascades are misregulated, diseases and metabolic disorders may occur. The identified mechanism may have a crucial influence on such signaling cascades.

Is keto a no no? Trending diet leads to increased risk of diabetes, suggests animal study

09 Aug 2018 --- Trending ketogenic diets, which are low carbohydrate high fat eating plans that are known to lead to weight loss, may cause an increased risk of Type 2 diabetes in the early stage of the diet, according to new research published in The Journal of Physiology. Zurich-based researchers showed that even though ketogenic diet fed animals appear healthy in the fasted state, they exhibit decreased glucose tolerance to a greater extent than high carbohydrate, high fat, western style diet (HFD) fed animals.

Metabolic syndrome scores: Gender differences in low-calorie diet benefits

08 Aug 2018 --- A low-calorie diet causes different metabolic effects in women than in men, a new Diabetes, Obesity and Metabolism study suggests. In the study of more than 2,000 overweight individuals with pre-diabetes who followed a low-calorie diet for 8 weeks, men lost significantly more body weight than women, and they had larger reductions in a metabolic syndrome score, a diabetes indicator, fat mass and heart rate.

Slendacor: Endorsement for study design on weight management solution

07 Aug 2018 --- PLT Health Solutions, Inc. has revealed the results of a clinical study the company helped develop has been published in the highly-regarded scientific journal, Diabetes, Obesity and Metabolism. Entitled “Efficacy of a novel herbal formulation for weight loss demonstrated in a 16‐week randomized, double‐blind, placebo‐controlled clinical trial with healthy overweight adults” (Dixit, et al. 2018), the publication describes clinical evaluation of Slendacor Weight Management Complex, which was introduced to the market in 2017.

Increased belly fat in older adults linked to cognitive impairment

06 Aug 2018 --- A higher waist to hip ratio has been linked to reduced cognitive function in older Irish adults (over 60 years of age) by a new study using data from over 5,000 individuals. These findings have significant implications as the global prevalence of dementia is predicted to increase from 24.3 million in 2001 to 81.1 million by 2040.

Study: Deep ocean water proven effective for weight management

31 Jul 2018 --- Deep sea water, which is filled with minerals, can exhibit anti-obesity effects, a study published in Marine Drugs has found, by regulating lipolysis, fatty acid oxidation and inflammation in rats fed a high-fat diet. The material used in the study was D-minneralz – which contains over 70 kinds of minerals and trace elements – from the Taiwan Yes Deep Ocean Water Company.

Why high-fiber diets don't always lead to weight loss: Study shows it depends on gut bacteria

23 Jul 2018 --- The increasingly popular fiber-rich “New Nordic Diet” might not work for everyone as its success depends on the particular combination of bacteria in the intestines of the dieter, according to a study in the International Journal of Obesity. In the era of personalized nutrition, the involved researchers note that there might be value in getting your stool tested and your gut bacteria counted before starting on a new diet. The results can be used to predict whether a particular diet will work for you.

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